You can remove a USB controller from your virtual machine.
When you remove the USB controller, you cannot connect a USB device to the virtual machine.
Shut down or power off the virtual machine. You cannot change the setting while the virtual machine is powered on or suspended.
Select Window > Virtual Machine Library.
Select a virtual machine in the Virtual Machine Library window and click Settings.
Under Removable Devices in the Settings window, click USB & Bluetooth.
Under Advanced USB options, click Remove USB Controller.
Click Remove in the confirmation dialog box.